Helicase is an enzyme that is responsible for the separation of two strands of DNA from their double helix form. It leads the replication process by enabling access to the leading and lagging strands for primases, DNA polymerases, and other enzymes. Helicases break hydrogen bonds between nucleotide bases, which hold two strands together in the helix shape. The overall replication fork is created by the helicase.
What is the function of helicases?
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