What is the function of nucleases?

Nucleases cleave the phosphodiester bonds, which means they can remove nucleic acids from the DNA. The enzyme enables a precision-based modification of a DNA molecule on a single nucleotide. It is important for mismatch repair, nucleotide excision repair, base excision repair, and DNA replication. In other words, random single nucleotide mutations or alterations due to external or internal stressors, such as oxidative stress, can be reversed by the precision provided through nucleases.

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