In understanding the molecular mechanisms of the amphiphilic membrane-active peptides, the interactions of the peptides and the lipids bilayer’s under near-native situations are crucial. The composition of the amino acids greatly determines the non-particular features of the peptides in regard to the physicochemical features of the side chains. The outcoming impacts on the functional features of the peptides involve the impact on the conformation, binding affinities within the peptide interactive, and structural dynamics. The impact of the substituting oxidation-prone methionine (Met) with non-oxidizable norleucine (Nle) in a model of alpha-helical antimicrobial peptide PLla via a comparison done systematically of PGla and the mutant Met/2Nle.
By adding Norleucine in place of methionine in the peptide what happens to its ability to bind to Cu(I)?
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References
Academic.Tips. (2022) 'By adding Norleucine in place of methionine in the peptide what happens to its ability to bind to Cu(I)'. 15 November.
Reference
Academic.Tips. (2022, November 15). By adding Norleucine in place of methionine in the peptide what happens to its ability to bind to Cu(I)? https://academic.tips/question/by-adding-norleucine-in-place-of-methionine-in-the-peptide-what-happens-to-its-ability-to-bind-to-cui/
References
Academic.Tips. 2022. "By adding Norleucine in place of methionine in the peptide what happens to its ability to bind to Cu(I)?" November 15, 2022. https://academic.tips/question/by-adding-norleucine-in-place-of-methionine-in-the-peptide-what-happens-to-its-ability-to-bind-to-cui/.
1. Academic.Tips. "By adding Norleucine in place of methionine in the peptide what happens to its ability to bind to Cu(I)?" November 15, 2022. https://academic.tips/question/by-adding-norleucine-in-place-of-methionine-in-the-peptide-what-happens-to-its-ability-to-bind-to-cui/.
Bibliography
Academic.Tips. "By adding Norleucine in place of methionine in the peptide what happens to its ability to bind to Cu(I)?" November 15, 2022. https://academic.tips/question/by-adding-norleucine-in-place-of-methionine-in-the-peptide-what-happens-to-its-ability-to-bind-to-cui/.
Work Cited
"By adding Norleucine in place of methionine in the peptide what happens to its ability to bind to Cu(I)?" Academic.Tips, 15 Nov. 2022, academic.tips/question/by-adding-norleucine-in-place-of-methionine-in-the-peptide-what-happens-to-its-ability-to-bind-to-cui/.