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Neurobiology of Addiction Based on van Holst et al.’s Study
Discuss the neurobiology of addiction based on the study of van Holst et al.
Many addictive substances can lead to changes in dopamine levels in the brain. For example, both cocaine and alcohol are associated with elevated levels of baseline striatal dopamine. Although other neurotransmitter systems have been implicated, there is strong evidence that substance addiction primarily involves the dopamine (dopaminergic) system. The dopaminergic system also seems to play a key role in behavioral addictions, especially pathological gambling. What do the findings of van Holst et al. (2018) tell us about dopamine in the brains of pathological gamblers?