Metallothionein is a zinc storage protein whose transcriptional regulation is synced with ZNT1 (Zinc transporter 1). What is the function of ZNT1 and why might its transcription mirror metallothionein?

ZNT1 is a predominantly human cell plasma membrane protein responsible for transporting zinc inside the cell. Specifically, this protein regulates the flow of zinc (and calcium) inward, protecting the cell from excess cations. When zinc cations are abundant outside the cell, ZNT1 transcription is enhanced by MTF-1, affecting metallothionein. In other words, the increase in ZNT1 and metallothionein transcription is synchronized because the same transcription factor mediates it.

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Academic.Tips. (2022) 'Metallothionein is a zinc storage protein whose transcriptional regulation is synced with ZNT1 (Zinc transporter 1). What is the function of ZNT1 and why might its transcription mirror metallothionein'. 8 October.

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Academic.Tips. (2022, October 8). Metallothionein is a zinc storage protein whose transcriptional regulation is synced with ZNT1 (Zinc transporter 1). What is the function of ZNT1 and why might its transcription mirror metallothionein? https://academic.tips/question/metallothionein-is-a-zinc-storage-protein-whose-transcriptional-regulation-is-synced-with-znt1-zinc-transporter-1-what-is-the-function-of-znt1-and-why-might-its-transcription-mirror-metallothionein/

References

Academic.Tips. 2022. "Metallothionein is a zinc storage protein whose transcriptional regulation is synced with ZNT1 (Zinc transporter 1). What is the function of ZNT1 and why might its transcription mirror metallothionein?" October 8, 2022. https://academic.tips/question/metallothionein-is-a-zinc-storage-protein-whose-transcriptional-regulation-is-synced-with-znt1-zinc-transporter-1-what-is-the-function-of-znt1-and-why-might-its-transcription-mirror-metallothionein/.

1. Academic.Tips. "Metallothionein is a zinc storage protein whose transcriptional regulation is synced with ZNT1 (Zinc transporter 1). What is the function of ZNT1 and why might its transcription mirror metallothionein?" October 8, 2022. https://academic.tips/question/metallothionein-is-a-zinc-storage-protein-whose-transcriptional-regulation-is-synced-with-znt1-zinc-transporter-1-what-is-the-function-of-znt1-and-why-might-its-transcription-mirror-metallothionein/.


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Academic.Tips. "Metallothionein is a zinc storage protein whose transcriptional regulation is synced with ZNT1 (Zinc transporter 1). What is the function of ZNT1 and why might its transcription mirror metallothionein?" October 8, 2022. https://academic.tips/question/metallothionein-is-a-zinc-storage-protein-whose-transcriptional-regulation-is-synced-with-znt1-zinc-transporter-1-what-is-the-function-of-znt1-and-why-might-its-transcription-mirror-metallothionein/.

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"Metallothionein is a zinc storage protein whose transcriptional regulation is synced with ZNT1 (Zinc transporter 1). What is the function of ZNT1 and why might its transcription mirror metallothionein?" Academic.Tips, 8 Oct. 2022, academic.tips/question/metallothionein-is-a-zinc-storage-protein-whose-transcriptional-regulation-is-synced-with-znt1-zinc-transporter-1-what-is-the-function-of-znt1-and-why-might-its-transcription-mirror-metallothionein/.

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